A case of poisoning by oral lime sulfur / 中华劳动卫生职业病杂志

Lime sulfur is a common bactericide with strong alkalinity, and is highly corrosive to humans and animals. It is rare for lime sulfur poisoning clinically. This article discusses the clinical manifestations of a patient who was poisoned by oral lime sulfur. After the poisoning, the mucosa of the lips and pharynx broke, fever, and pulmonary inflammation quickly appeared. The pulmonary CT showed slight interstitial changes in both lungs. Through high flow oxygen inhalation, fluid infusion, drainage, maintenance of water and electrolyte balance, protection of important organ functions, and other symptomatic support and treatment, as well as control of blood pressure, blood sugar, maintenance of circulatory function and other targeted measures, the patient's condition gradually improved.

Effect of progesterone on expression of brain tissue damage factors and anti damage factors in neonatal rats with hypoxic-ischemic brain damage / 中华实用儿科临床杂志

Objective To study the effect of progesterone on tumor necrosis factor (TNF-α),interleukin-1β (IL-1β),nerve growth factor(NGF) and brain derived neurotrophic factor(BDNF) expression in the cortex and hippocampus tissue in newborn rats with hypoxic-ischemic brain damage (HIBD),and to discuss the protective molecular mechanism of progesterone on HIBD in neonatal rats.Methods Forty-eight 7-day-old neonatal rats were randomly divided into 3 groups:sham-operated group,hypoxic-ischemic group and pretreatment group.Rats in hypoxic-ischemic group and pretreatment group were subjected to left common carotid artery ligation,then they were exposed to 80 mL/L oxygen and 920 mL/L nitrogen gas in the closed container at 37 ℃ for up to 2.5 h to establish HIBD models.Progesterone was injected intraperitoneally into the rats in the pretreatment group 30 min before hypoxia,and solution was injected into the first 2 groups.All the rats were killed at the 24 h after operation.The levels of TNF-α,IL-1β,NGF,BDNF were measured by enzyme linked immunosorbent assay and the expressions of TNF-α,IL-13,NGF,BDNF mRNA were analyzed by reverse transcription-polymerase chain reaction.Results The contents of TNF-α,IL-1β,NGF,BDNF and their mRNA expressions in hypoxic-ischemic group were significantly higher than those in the sham-operated group.In pretreatment groups,the levels of TNF-α,IL-1β and their mRNA expressions were significantly lower than those in hypoxic-ischemic group.The levels of NGF,BDNF and their mRNA expressions in pretreatment group were significantly higher than those in hypoxic-ischemic group (all P ＜ 0.05).Conclusions Progesterone exerts neuroprotective effect on hypoxic-ischemic encephalopathy-induced brain damage,and the action mechanism is related to down-regulate the expression of damage factor and up-regulate the expression of anti damage factor.

Observation on short and long-term effects of cervical spondylotic radiculopathy treated with abdominal acupuncture plus Long's bone-setting manipulation / 中国针灸

<p><b>OBJECTIVE</b>To compare the short and long-term therapeutic effects on cervical spondylotic radiculopathy (CSR) treated with simple Long's bone-setting manipulation, abdominal acupuncture and abdominal acupuncture plus Long's bone-setting manipulation.</p><p><b>METHODS</b>One hundred and eighty cases of CSR were randomly allocated into abdominal acupuncture plus bone-setting group (combined therapy group), bone-setting group and abdominal acupuncture group, 60 cases in each group. In combined therapy group, the abdominal acupuncture and Long's bone-setting were applied in combination. Abdominal acupuncture was applied to Zhongwan (CV 12), Guanyuan (CV 4), Shiguan (KI 18), Shangqu (KI 17), etc. Long's manipulation, such as bone-setting in head-upward posture and bone-setting in head-lateral posture, was adopted. In bone-setting group and abdominal acupuncture group, Long's bone-setting manipulation and abdominal acupuncture were adopted simply and respectively. The clinical therapeutic effects were compared after 2 courses of treatment (short-term) and 1-month after treatment (long-term) among groups.</p><p><b>RESULTS</b>The short and long-term curative and markedly effective rates in combined therapy group were 80.7% (46/57) and 68.4% (39/57) respectively, which were better than those of 63.64% (35/55), 30.9% (17/55) in bone-setting group and 58.9% (33/56), 50.0% (28/56) in abdominal acupuncture group, separately (all P < 0.05). Moreover, the long-term curative and markedly effective rate in abdominal acupuncture group was superior to that in bone-setting group (P < 0.05).</p><p><b>CONCLUSION</b>Abdominal acupuncture plus Long's bone-setting manipulation has significant efficacy of either short or long-term on CSR, which is superior to the efficacy of either simple abdominal acupuncture or Long's bone-setting manipulation and indicates superimposed effect. Hence, it is one of the better approaches in CSR treatment.</p>

Relationship between acute pancreatitis and systemic inflammation response syndrome in children / 中国当代儿科杂志

<p><b>OBJECTIVE</b>To study the clinical features of children with acute pancreatitis complicated by systemic inflammatory response syndrome (SIRS).</p><p><b>METHODS</b>Clinical data of 71 children with acute pancreatitis from May 2005 to June 2007 were retrospectively studied. According to complications with or without SIRS, the patients were classified into two groups: SIRS (n=30) and non-SIRS (n=41). The SIRS group was subdivided into three groups based on the item number consistent with SIRS diagnostic criteria: S1 (2 items), S2 (3 items) and S3 (4 items).</p><p><b>RESULTS</b>More patients had severe abdominal pain (n: 12 vs 3) and fever (n: 25 vs 15) in the SIRS group than in the non-SIRS group (p<0.01). The serum C-reactive protein (CRP) levels (49.61+/-8.09 mg/L) in the SIRS group were significantly higher than those in the non-SIRS group (7.98+/-2.82 mg/L) (p<0.01). The serum calcium level (1.93 mol/L) in the SIRS group was statistically lower than that in the non-SIRS group (2.81 mol/L)(p<0.01). Among the SIRS group, the S3 group showed the highest CRP level (120.40+/-10.04 mg/L), followed by the S2 group (75.78+/-9.50 mg/L) and S1 group (28.51+/-8.51 mg/L) (p<0.01). The highest sensitivity (50%) and negative predictive value (96.8%) for the diagnosis of severe acute pancreatitis was obtained for a CRP cut-off at 110 mg/L. The imaging changes were more severe in the SIRS group than in the non-SIRS group.</p><p><b>CONCLUSIONS</b>Severe abdominal pain and fever were common clinical symptoms in children with acute pancreatitis complicated by SIRS. Serum CRP and calcium levels as well as imaging changes are important markers for the severity evaluation of acute pancreatitis. The patients with serum CRP level above 110 mg/L or with more than three items consistent with SIRS diagnostic criteria are at high risk for the development of severe acute pancreatitis.</p>

Clinical observation on auricular-plaster therapy combined with chiropractics for treatment of emaciation in children / 中国针灸

<p><b>OBJECTIVE</b>To search for a non-medicine therapy for infant emaciation.</p><p><b>METHODS</b>The observation group of 55 cases were treated with auricular point sticking combined with chiropractics. For the auricular point sticking therapy, vaccaria seeds were stuck at 9 points such as small intestine, Shenmen, spleen, endocrine, and others, and replaced once every 5 days, 10 days constituting one course. Chiropractics: knead or massage the muscles from lumbosacral area upward to Dazhui (GV 14). The control group were treated with oral administration of pepsin mixture, 10 mL after meals, thrice each day. They were treated for 5 courses.</p><p><b>RESULTS</b>Of the 55 cases in the observation group, 7 were cured, 20 markedly effective, 24 effective and 4 ineffective, with a total effective rate of 92.7%, and among the 23 cases in the control group, 2 cases were cured, 7 markedly effective, 8 effective and 6 ineffective, with a total effective rate of 73.9%.</p><p><b>CONCLUSION</b>Auricular point sticking combined with chiropractics is a better non-medicine therapy for emaciation in children.</p>

Effect of Progesterone on Progesterone Receptor in Brain Tissue with Hypoxia-Ischemia Brain Damage in Neonatal Rats / 实用儿科临床杂志

ObjectiveTo observe the effect of progesterone on progesterone receptor in brain tissue with hypoxia-ischemia brain da-mage(HIBD) in neonatal rats,and discuss the protective mechanism of progesterone on HIBD of neonatal rats.MethodsTwenty-four 7-day-old neonatal rats were randomly divided into 3 groups:sham-operated group,hypoxia-ischemia group and pretreatment group.Rats in hypoxia-ischemia group and pretreatment group were subjected to left common carotid artery ligation,then were exposed to 80 mL/L oxygen and 920 mL/L nitrogen gas in 37 ℃ closed container for up to 2.5 h to establish hypoxia-ischemia encephalopathy(HIE) model.Progestero-ne was injected intraperitoneally into pretreatment group rats respectively at 30 minutes before hypoxia,solution was injected into the first 2 groups.All rats were killed at the 24 hour after operation,immunohistochemistry staining was used to examine the expression of progesterone receptor in brain.ResultsTotally 24 neonatal rats entered the result analysis without loss.Progesterone receptor was expressed in both endochylema and nucleus in every group rat.The amount of the positive cell of progesterone receptor in hypoxia-ischemia group significantly decreased compared with that in sham-operated group(P

Effect of Progesterone on Neuronal Apoptosis and Nitric Oxide Level in Cortex and Hippocampus of Newborn Rats with Hypoxic-Ischemic Encephalopathy / 实用儿科临床杂志

Objective To explore the effect of progesterone on the rate of neuronal apoptosis and nitric oxide(NO) level in the cortex and hippocampus tissue of newborn rats with hypoxic-ischemic encephalopathy(HIE).Methods Thirty 7-day-old neonatal rats were randomly divided into 3 groups:sham-operated group,hypoxic-ischemic(HI) group and pretreatment group.Rats in HI group and pretreatment group were subjected to left common carotid artery ligation,then were exposed to 80 mL/L oxygen and 920 mL/L nitrogen gas in 37 ℃ closed container for up to 2.5 h to establish HIE model.Progesterone was injected intraperitoneally into rats in the pretreatment group respectively for 30 minutes before hypoxia,and solution was injected into the sham-operated group and HI group.All rats were killed at 24 h after operation.The neuron apoptosis was identified and analyzed by flow cytometry.Nitrate/nitrite was assayed to represent nitric oxide content of brain tissues.Results The ratio of neuronal apoptosis and NO contents in cortex and hippocampus tissue in HI group [(10.09?0.36)%,(12.32?0.28)%,(51.36?9.71) ?mol/L,(52.34?4.26) ?mol/L] were significantly higher than those in sham-operated group [(2.49?0.23)%,(2.58?0.26)%,(18.16?6.24) ?mol/L,(19.28?3.58) ?mol/L)](P_a

Influence of Reducing Fat on Sex Hormone and Growth Hormone in Adolescent Girl Students with Simple Over weight and Obesity / 实用儿科临床杂志

Objective To investigate the effect of comprehensive intervention therapy of reducing fat on sex hormone and growth hormone(GH) in adolescent girl students with simple overweight and obesity.Methods Girl students with simple obesity were accepted a comprehensive measures composed of aerobicexercise,reasonable diet,behavior modification for 10 monthes,and their sex hormone and GH were detected and analyzed before,during and after test respectively.Results GH and estradiol(E_2) levels were significantly lower in obese subjects than those in normal subjects,but the level of testosterone(T) was highter,and GH and E_2 were increased obviously after reducing fat.Level of T decreased significantly(P

Effect of Comprehensive Intervention Therapy of Losing Weight on Blood Leptin,Blood Lipid,Blood Glucose,Insulin in Adolescent Girl Students with Simple Obesity / 实用儿科临床杂志

Objective To investigate the effect of comprehensive intervention therapy of losing weight on leptin and blood lipid,blood glucose,insulin in adolescent girl students with simple obesity.Methods Simple obesity adolescent girl students were accepted the losing weight therapy composed of the aerobic exercise,reasonable diet,behavior modification and medical supervision for 10 months.Then the changes of blood leptin and correlated hormone were examined before test,during test and after test,respectively.Results The leptin and correlated hormone levels were significantly higher in obesity subjects than that in normal subjects,and the levels of serum leptin was positively correlated with BMI and insulin.The blood leptin and blood lipid,blood glucose,insulin were decreased obviously after experimental losing weight.Conclusion Comprehensive intervention therapy of losing weight can significantly lose weight,leptin and insulin,so it plays an important role in modifying the metabolism disorder

Protective Effect of Progesterone on Brain Edema in Newborn Rats with Hypoxic-Is chemic Encephalopathy / 实用儿科临床杂志

Objective To observe the protective effect of progesterone on brain edema in newborn rats with hypoxic-ischemic encephalopathy(HIE).Methods Fifty-two 7-day-old neonatal rats were randomly divided into 5 groups:normol control group(group A),hypoxic-ischemic group (group B) and pretreatment groups(group C,D and E).Rats were subjected to left common carotid artery ligation,then were exposed to 8% oxygen and 92% nitrogen for 2.5 hours to establish HIE model.Progesterone was injected intraperitoneally into the groups C,D and E rats respectively at 30 minutes before hypoxia.All rats were killed at the 24 hours after operations,then the contents of water,sodium,potassium were mensurated. Results The contentation of water in group B was higher than that in group A,the contentation of water,sodium in groups C,D and E were significantly lower compared with group B, but the contents potassium were no difference between group C,E and B. Conclusion Progesterone exerts a prominent preventive and protetive effects on the hypoxic ischemic brain edema in newborn rats.